Wayne Casserole 🌮🥘

By: Rabia

A hearty, Tex-Mex-inspired casserole layered with biscuits, creamy topping, and plenty of flavor — family-friendly and crowd-pleasing!

📝 Recipe Card

Hook

Wayne Casserole – Layers of seasoned beef, biscuits, and a creamy sour cream-mayo topping make this retro-style casserole a weeknight winner. Comfort food with a Tex-Mex twist!

Servings & Timing

  • Servings: 6–8

  • Prep Time: 20 minutes

  • Cook Time: 30 minutes

  • Total Time: 50 minutes

Dietary Badges

🥘 Family Dinner | 🌮 Tex-Mex-Inspired | 🧀 Comfort Food

Ingredients

  • 1 pound ground beef

  • 1 medium onion, chopped

  • 1 medium bell pepper, chopped

  • 1 (10-oz) can diced tomatoes with green chilies (like Rotel), drained

  • 1 packet taco seasoning

  • 1 (8-oz) can refrigerated biscuits

  • 1 cup sour cream

  • 1 cup mayonnaise

  • 2 cups shredded cheddar cheese (or Mexican blend)

Instructions

  1. Cook Beef Mixture: In a skillet, cook ground beef with onion and bell pepper until meat is browned and vegetables are tender. Drain excess fat.

  2. Season: Stir in taco seasoning and diced tomatoes with green chilies. Simmer for 5 minutes.

  3. Prepare Biscuits: Preheat oven to 350°F (175°C). Grease a 9×13-inch baking dish. Cut biscuits into quarters and spread evenly across the bottom of the dish.

  4. Layer: Spread beef mixture over biscuits. In a separate bowl, mix sour cream and mayonnaise. Spread evenly over beef layer.

  5. Top with Cheese: Sprinkle shredded cheddar over the creamy layer.

  6. Bake: Bake uncovered for 25–30 minutes, until biscuits are golden and cheese is bubbly.

  7. Serve: Let rest 5 minutes before slicing. Serve with fresh toppings if desired.

Brief Introduction

This Wayne Casserole is a tried-and-true family recipe — the kind of dish that shows up at church potlucks, game day parties, or weeknight dinners. It’s creamy, cheesy, a little spicy, and incredibly satisfying.

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Ingredient Notes & Substitutions

  • Ground Beef: Swap with ground turkey or chicken for a lighter version.

  • Biscuits: Use crescent roll dough or homemade biscuit dough if preferred.

  • Cheese: Monterey Jack or pepper jack adds extra creaminess and spice.

  • Toppings: Fresh tomatoes, jalapeños, or green onions make great garnishes.

Variations & Serving Suggestions

  • Spicy Kick: Add chopped jalapeños or a dash of hot sauce to the beef mixture.

  • Layered Tex-Mex: Add a can of drained black beans or corn for extra heartiness.

  • Serving Ideas:

    • With a side salad 🥗

    • Over shredded lettuce for a taco-salad-style plate

    • With tortilla chips for scooping

Storage & Reheating

  • Fridge: Store covered for up to 3 days.

  • Reheat: Warm in oven at 325°F until heated through, or microwave in portions.

  • Freezer: Freeze before baking (wrapped tightly) for up to 2 months. Thaw overnight in fridge, then bake as directed.

FAQs

Q: Can I make this ahead of time?
A: Yes — assemble casserole up to the sour cream-mayo layer, cover, and refrigerate. Add cheese just before baking.

Q: Do the biscuits get soggy?
A: Nope! Baking them first under the beef mixture keeps them fluffy and golden.

Q: Can I use Greek yogurt instead of sour cream?
A: Yes, but the flavor will be tangier and texture a bit lighter.

Personal Note

This casserole is pure comfort food nostalgia. The mix of biscuits, creamy topping, and melty cheese is dangerously addictive — don’t be surprised if your family asks for seconds.

Call to Action

If you try this Wayne Casserole, let me know how you layered yours! ⭐ Did you stick with the classic, or add your own Tex-Mex spin with beans, jalapeños, or extra cheese?

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Rabia
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